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Omega-3 Poly-Unsaturated Fatty Acids for the Prevention of Severe Neutropenic Enterocolitis in Patie

Severe leukopenia in Staphylococcus aureus-necrotizing, community-acquired pneumonia: risk factors a

Antimicrobials and renal failure in neutropenic patients

Neutropenic Enterocolitis in a Child with Acute Myeloid Leukemia Successfully Treated with Early Sur

Inpatient versus outpatient management of neutropenic fever in gynecologic oncology patients: Is ris

Feasibility of early discharge strategies for neutropenic fever: outcomes of a Victorian organisatio

A hematology consensus agreement on antifungal strategies for neutropenic patients with hematologica

The Anti-Pseudomonas aeruginosa Antibody Panobacumab Is Efficacious on Acute Pneumonia in Neutropeni

Candidaemia in the non-neutropenic patient: A critique of the guidelines

71-year old woman with neutropenic fever during chemotherapy

Sirolimus: A Switch Option for Mycophenolate Mofetil-Induced Leukopenia in Renal Transplant Recipien

Imipenem versus piperacillin/tazobactam for empiric treatment of neutropenic fever in adults

Implementation of risk stratified antibiotic therapy for neutropenic fever: what are the risks?

Impact of vancomycin resistance on mortality in neutropenic patients with enterococcal bloodstream i

Breakthrough bacteremia due to Clostridium tertium in a patient with neutropenic fever, and identifi

The significance of serum urokinase plasminogen activation receptor (suPAR) in the diagnosis and fol

Empirical voriconazole therapy for febrile neutropenic patients with hematological disorders: a pros

Intravenous itraconazole against experimental neutropenic Candida parapsilosis infection: efficacy a

European guidelines for empirical antibacterial therapy for febrile neutropenic patients in the era

The impact of cefepime as first line therapy for neutropenic fever on Clostridium difficile rates am

應用抗甲狀腺藥物致粒細胞缺乏患者感染的臨床研究
作 者:任蕾,秦貴軍,鄭麗麗,張會娟,孫良閣,段宇

中華醫院感染學雜志 2014年第24卷第17期

【摘要】目的 分析使用抗甲狀腺藥物(ATD)引起粒細胞缺乏及引發感染患者的臨床特點和感染部位、病原菌分布及其耐藥性。 方法 回顧性分析72例使用ATD引起粒細胞缺乏及引發感染患者的臨床資料,采用SPSS11.0 軟件進行統計分析。 結果 72例患者感染部位以呼吸道為主,占55.3%,其次為泌尿系、胃腸道,分別占21.1% 和10.5%;共分離出病原菌52株,其中革蘭陽性菌20株占38.5%;革蘭陰性菌26株占50.0%;真菌6株占 11.5%;革蘭陽性菌對萬古霉素和替考拉寧敏感性最高,分別為90.0%和100.0%,對其他抗菌藥物均存在不同 程度的耐藥性;革蘭陰性菌對美羅培南和亞胺培南敏感性最高,均為92.3%,對第三代頭孢類藥物、阿米卡星等 存在不同程度的耐藥性。結論!使用 ATD容易引起患者粒細胞缺乏,繼而誘發各種感染,且感染部位以呼吸道 最為常見,引起感染的病菌中革蘭陰性菌與革蘭陽性菌相當,真菌感染相對較少。

【關鍵詞】抗甲狀腺藥物;粒細胞缺乏;感染

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