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Antibiotic Use Before Chemotherapy: A Risk Factor for Developing Neutropenic Colitis in Children Wit

Febrile Neutropenic Infection Occurred in Cancer Patients Undergoing Autologous Peripheral Blood Ste

Epidemiology and outcome of bacteraemia in neutropenic patients in a single institution from 1991-20

Extended-Spectrum beta-Lactamase-Producing Escherichia coli and Klebsiella pneumoniae Bacteremia in

Human plasma cell-free DNA as a predictor of infectious complications of neutropenic fever in hemato

Pneumonia in the neutropenic cancer patient

Association between early peak temperature and mortality in neutropenic sepsis

Economic evaluation of a preemptive treatment strategy for invasive fungal infection in neutropenic

An update to the cost-effectiveness of posaconazole vs fluconazole or itraconazole in the prevention

Moxibustion for the treatment of chemotherapy-induced leukopenia: a systematic review of randomized

Invasive Aspergillosis in Neutropenic Patients During Hospital Renovation: Effectiveness of Mechanic

Immune reconstitution inflammatory syndrome in neutropenic patients with invasive pulmonary aspergil

Different clinical presentation of community-onset bacteremia among neutropenic adults in the ED

應用抗甲狀腺藥物致粒細胞缺乏患者感染的臨床研究
作 者:任蕾,秦貴軍,鄭麗麗,張會娟,孫良閣,段宇

中華醫院感染學雜志 2014年第24卷第17期

【摘要】目的 分析使用抗甲狀腺藥物(ATD)引起粒細胞缺乏及引發感染患者的臨床特點和感染部位、病原菌分布及其耐藥性。 方法 回顧性分析72例使用ATD引起粒細胞缺乏及引發感染患者的臨床資料,采用SPSS11.0 軟件進行統計分析。 結果 72例患者感染部位以呼吸道為主,占55.3%,其次為泌尿系、胃腸道,分別占21.1% 和10.5%;共分離出病原菌52株,其中革蘭陽性菌20株占38.5%;革蘭陰性菌26株占50.0%;真菌6株占 11.5%;革蘭陽性菌對萬古霉素和替考拉寧敏感性最高,分別為90.0%和100.0%,對其他抗菌藥物均存在不同 程度的耐藥性;革蘭陰性菌對美羅培南和亞胺培南敏感性最高,均為92.3%,對第三代頭孢類藥物、阿米卡星等 存在不同程度的耐藥性。結論!使用 ATD容易引起患者粒細胞缺乏,繼而誘發各種感染,且感染部位以呼吸道 最為常見,引起感染的病菌中革蘭陰性菌與革蘭陽性菌相當,真菌感染相對較少。

【關鍵詞】抗甲狀腺藥物;粒細胞缺乏;感染

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