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Comparison of anidulafungin's and fluconazole's in vivo activity in neutropenic and non-neutropenic

Lethal human neutropenic entercolitis caused by Clostridium chauvoei in the United States: Tip of th

Management of neutropenic enterocolitis in children with cancer

Efficacy and safety of micafungin as an empirical antifungal therapy for suspected fungal infection

Pharmacodynamics of TD-1792, a Novel Glycopeptide-Cephalosporin Heterodimer Antibiotic Used against

Clinical features and outcomes of Staphylococcus aureus infections in non-neutropenic cancer patient

Analysis of leukopenia and anemia after gastric bypass surgery

Clozapine-induced late leukopenia

Bacteraemia due to Eikenella corrodens secondary to periodontal infection in a neutropenic patient

Successful treatment of NDM-1 Klebsiella pneumoniae bacteraemia in a neutropenic patient

The shape of the myelosuppression time profile is related to the probability of developing neutropen

Rectal Involvement in Neutropenic Enterocolitis

Why is My Patient Neutropenic?

Cost-effectiveness of posaconazole versus fluconazole or itraconazole in the prevention of invasive

Prospective study in critically ill non-neutropenic patients: diagnostic potential of (1,3)-beta-D-g

Preterm neonates show marked leukopenia and lymphopenia that are associated with increased regulator

Diagnostic yield of bronchoscopic sampling in febrile neutropenic patients with pulmonary infiltrate

Antibody specific to thioredoxin reductase as a new biomarker for serodiagnosis of invasive aspergil

Comparative Effectiveness of Filgrastim, Pegfilgrastim, and Sargramostim as Prophylaxis Against Hosp

Demographics, morbidity, and mortality febrile neutropenic adult patients treated with cefepime

作 者:任蕾,秦貴軍,鄭麗麗,張會娟,孫良閣,段宇

中華醫院感染學雜志 2014年第24卷第17期

【摘要】目的 分析使用抗甲狀腺藥物(ATD)引起粒細胞缺乏及引發感染患者的臨床特點和感染部位、病原菌分布及其耐藥性。 方法 回顧性分析72例使用ATD引起粒細胞缺乏及引發感染患者的臨床資料,采用SPSS11.0 軟件進行統計分析。 結果 72例患者感染部位以呼吸道為主,占55.3%,其次為泌尿系、胃腸道,分別占21.1% 和10.5%;共分離出病原菌52株,其中革蘭陽性菌20株占38.5%;革蘭陰性菌26株占50.0%;真菌6株占 11.5%;革蘭陽性菌對萬古霉素和替考拉寧敏感性最高,分別為90.0%和100.0%,對其他抗菌藥物均存在不同 程度的耐藥性;革蘭陰性菌對美羅培南和亞胺培南敏感性最高,均為92.3%,對第三代頭孢類藥物、阿米卡星等 存在不同程度的耐藥性。結論!使用 ATD容易引起患者粒細胞缺乏,繼而誘發各種感染,且感染部位以呼吸道 最為常見,引起感染的病菌中革蘭陰性菌與革蘭陽性菌相當,真菌感染相對較少。